Create > Constraints > Equal Constraints prompts you with the following dialog.
It allows you to define a generic constraint at one or two nodes. An equal displacement constraint is one type of multi-DOF constraint.
A regular support and multi-DOF constraints may be applied on the same node as long as the support/constrained directions do not interfere with each other.
Multi-DOF constraint forces and moments are listed separately from the regular support reactions in the analysis results.